On the one hand, the hypothesis advancing the existence of infected cells exhibiting a decay dynamic that is different from short-lived CD4 cells has literature support.[1, 9] On the other hand, the hypothesis stipulating that such cells have a negligible impact on virion production and completely attributing the slower decay of virion production to new short-lived cell infections in a drug limited compartment finds long term inconsistencies. Here, CD4 is linked to infection.