Protein-folding diseases are related to chaperone defects such as DNAJC12 and DNAJC6, involved in neurotransmitter disturbances and a spectrum of symptoms including early Parkinsonism (and hyperphenylalaninemia in the case of DNAJC12 (Anikster et al. 2017)). The gene discussed is DNAJC12; the disease is Parkinsonism.