IL4 and asthma: To explore the differences among asthmatic patients in different conditions, these subjects were divided into the well-controlled group and partly/uncontrolled group according to the ACQ-7 questionnaire, and it was found that IL-4 producing Treg cells were increased in the partly/poorly controlled group rather than in the well-controlled group, which means IL-4 may play a direct role in the development of asthma and affect the treatment effect of asthma.