In both Clostridium difficile and Enterococcus faecalis infection, auranofin has been shown to reduce selenium concentration and prevent production of selenoproteins, like in the case of glycine reductases (Jackson et al., 2006; Srivastava et al., 2011; Roder and Thomson, 2015). The gene discussed is SELENOS; the disease is Enterococcus faecalis infection.