Concordant with our results, CASC15 was found to affect the tumorigenesis of gastric cancer by regulating CDKN1A via interaction with EZH2 and WDR5 in nucleus, meanwhile, CASC15 participated in gastric cancer progression by modulating ZEB1 expression through sponging miR-33a-5p in cytoplasm [15]. Here, CDKN1A is linked to gastric cancer.