However, odds ratio analysis showed that subjects with TT homozygous rs721917 alleles had an increased risk of susceptibility to TB (OR = 1.95, P = 0.045; Table 2), as the homozygous methionine amino acid at SP-D polypeptide position 11 was more frequent in TB patients than in non-TB subjects. This evidence concerns the gene SFTPD and tuberculosis.