Early signs that make diagnosis of HNF1A-MODY (in contrast to type 1 diabetes) possible include family history of diabetes, manifestation of diabetes without DKA, absence of islet antibodies, detectable C-peptide levels; similarly, younger age <30 years (11), lower BMI, presence of hypertension and triglycerides (15), higher HDL-cholesterol (>1.3 mmol/L) (16), eventually non-elevated fasting C-peptide level and marked sensitivity to SUR/sulphonylurea derivatives (5) are more indicative for HNF1A-MODY compared to type 2 diabetes. This evidence concerns the gene HNF1A and hypertensive disorder.