Nanog is overexpressed in cancer cells (Jeter et al., 2009, 2011; Pan et al., 2010; Zbinden et al., 2010; Du et al., 2012, 2013; Shan et al., 2012; Zhang et al., 2013; Wang et al., 2017) and in this study, we found that Nanog is overexpressed in CD34+ cells of patients with AML and in CD34+CD38- cells of leukemia cell lines. Here, NANOG is linked to leukemia.