After the acute phase, the TNF-α concentration decreased, but the IL-6 concentration increased, indicating that the inflammation reactions changed during different stroke phases; in particular, the TNF-α concentration was negatively correlated with the absolute number of CD4+ naïve T cells and the absolute number of CD4+ TEMRA cells, and the concentration of IFN-r was positively correlated with the absolute number of CD4+ T TEMRA cells, which indicated that changes in inflammation reactions accompanied the CD4+ T cell alterations. The gene discussed is TNF; the disease is Stroke.