Since there are β1 and γ2 but limited δ and little γ1 in the hippocampus available for β2 replacement67, insufficient or unsatisfactory replacement of β2 by other subunits in some hippocampal GABAA receptors in the event of a β2 deficit could represent a significant factor of defective hippocampal function in schizophrenia or in the Gabrb2 KO mice. Here, GABRB2 is linked to schizophrenia.