GABRB2 and schizophrenia: In conclusion, the advantage of the GABRB2-origin theory of schizophrenia resides in the multiplicity of its supportive evidence: (a) The SNPs in the vicinity of the AluYi6AH-151 insertion of GABRB2 were correlated with schizophrenia with odds ratios of 1.93–2.50, and also with both total β2 subunit and its long-to-short isoform ratio, indicating that their associations with schizophrenia arose directly from their regulation of β2 expression and alternative splicing7–15.