GABRB2 and schizophrenia: In agreement with schizophrenia genomics, Figs. 1 to 5 show that the Gabrb2 KO mice exhibited behavioral and cognitive changes similar to those observed in schizophrenia, including: neuroinflammation with increased oxidative stress43, increased pro-inflammatory cytokines44, and microglial activation45–47, as well as the comorbidities of hyperactivity48, decreases in cell proliferation in hippocampus4,49,50, and epilepsy40,41.