GABRB2 and schizophrenia: Accordingly, the observed decreases in newborn neurons, PV-positive interneurons and astrocytes, and increases in microglia (Figs. 4 and 5) may be expected to alter significantly the interactions between interneurons, astrocytes and microglia, giving rise to regional neuroinflammation and development of schizophrenia-like and comorbid phenotypes in the Gabrb2-knockout mice.