GABRB2 and schizophrenia: Significant decreases in PPI were observed in KO relative to WT for the 77–110, 77–120, and 83–110 dB prepulse-pulse combinations, in HT for only the 77–110 dB combination (Fig. 2c), and in neither KO nor HT for the 83–120 dB combination (Supplementary Fig. S1c), indicating that reduced copies of Gabrb2 brought about sensorimotor gating deficits resembling those observed in schizophrenia.