PPARG and hypertensive disorder: PPARγ is expressed predominantly in the adipose tissue where, together with the coexpression of C/EBP alpha and other proteins involved in lipid and glucose metabolism, serves as a key regulator both of adipocyte differentiation and triglyceride energy stores, and has pleiotropic vascular effects that are independent of its glucose blood-lowering effect, protecting against the progression of hypertension and atherosclerosis [17,18].