It could be due to two reasons: first, since neuroblastoma has a low genetic alteration frequency and a highly heterogeneous alteration spectrum, the common driver genes for the whole 145 patients may not exist; second, due to the potential mislabeling problem in aCGH data, CNAs detected in some patients may be incorrect, especially for the patients in low-risk group without MYCN amplification (The mislabel samples are identified utilizing MYCN alteration status. The gene discussed is MYCN; the disease is neuroblastoma.