Accordingly, Stacey et al., in their GWAS made up of 6145 BC cases and 33016 controls, identified two SNPs (rs4415084 and rs1094179) on 5p12, which conferred a risk in developing BC, especially in Estrogen Receptor Positive (ER) + BC (p = 1.3 × 10−17) [76]. Here, ESR1 is linked to breast cancer.