There is evidence that seaweed ingestion can control obesity, for instance a mixture of brown seaweed and pomegranate seed, called xanthigen showed anti-obesity activity through inhibition of peroxisome proliferator-activated receptor γ (PPARγ) expression and activation of the AMP-activated protein kinase (AMPK) phosphorylation [77]. This evidence concerns the gene PPARG and obesity due to melanocortin 4 receptor deficiency.