Tumor antigens from nearly 5000 breast cancer patients at early stages were detected using NAPPA, and 28 antigens were found to be highly responsive to their relevant autoantibodies: ATP6AP1, PDCD6IP, DBT, CSNK1E, FRS3, RAC3, HOXD1, SF3A1, CTBP1, C15orf48, MYOZ2, EIF3E, BAT4, ATF3, BMX, RAB5A, UBAP1, SOX2, GPR157, BDNF, ZMYM6, SLC33A1, TRIM32, ALG10, TFCP2, SERPINH1, SELL, and ZNF510 [91]. Here, SOX2 is linked to neoplasm.