The panel of SEREX-defined immunogenic tumor antigens include Cancer/Testis Antigens (CTAs, e.g., NY-ESO-1, SSX2, MAGE), mutational antigens (e.g., p53), differentiation antigens (e.g., tyrosinase, SOX2, ZIC2), and embryonic proteins [52]. Here, SOX2 is linked to neoplasm.