CUX1 transcriptionally activates the FGF1 gene in Hs578T human breast cancer cells.21 However, FGF reveals no difference in response to CUX1 expression in Bon‐1 pancreatic neuroendocrine cancer cells.15 To elucidate the DPPA induced anti‐angiogenic phenotype, we assessed a human angiogenesis gene array at the mRNA level using DPPA‐treated HUVECs. This evidence concerns the gene FGF1 and breast cancer.