We have shown that loss of S100A10 protein results in the inhibition of invasiveness in HT‐1080 fibrosarcoma (Choi et al., 2003) and Colo222 colorectal cancer cells (Zhang et al., 2004) and decrease in in vivo tumor growth of Lewis lung carcinoma (LLC) cells (Phipps et al., 2011). The gene discussed is S100A10; the disease is colorectal cancer.