CDK6 and neoplasm: Piao et al. [27] found that cationic NLCs could deliver miR-107 into tumor cells, and the clonogenic survival, cell invasion and cell migration of HNSCC cells were suppressed in delivery of miR-107 by cationic NLCs group compared with those in free miR-107 group, accompanied by decreased expression of tumor growth-related factor, such as protein kinase Cε (PKCε), cyclin-dependent kinase 6 (CDK6) and hypoxia-inducible factor 1-β (HIF1-β).