BRCA1 and neoplasm: We also noted additional BRCA1 mutant tumour cell lines (MDAMB436, HCC1395) and a BRCA1 promoter hypermethylated tumour cell line HCC3814 to display PARPi sensitivity, as did a number of synovial sarcoma tumour cell lines (SYO1, CME, HS-SYII, ASKA), as described earlier (Fig. 2E–G).