For example, MKEY was shown to suppresses abdominal aortic aneurysm formation and progression, reducing aortic diameter enlargement, preserving medial elastin fibres and smooth muscle cells, and attenuating mural macrophage infiltration, angiogenesis, and aortic metalloproteinase 2 and 9 expression24. Here, ELN is linked to abdominal aortic aneurysm.