The results showed that in both male and female UTX-knockout Eμ-Myc mice, lymphomas originated exclusively from later stage B cells (pre-B and immature/mature B cell), whereas UTX wild-type Eμ-Myc lymphomas also originated from early stage B cells (stem cell and pro-B cell) (Fig. 1g, Supplementary Fig. 2). Here, KDM6A is linked to lymphoma.