PC and metabolic dysfunction-associated steatotic liver disease: Seventy-four differentially methylated CpG sites (FDR < 0.004) were found in comparisons of the four phenotypic groups with NAFLD-specific methylation and expression differences observed for nine genes: ACLY (ATP citrate lyase), GALNTL4 (polypeptide N-acetylgalactosaminyltransferase 18), GRID1 (glutamate ionotropic receptor delta type subunit 1), IGF1 (insulin like growth factor 1), IGFBP2 (insulin like growth factor binding protein 2), IP6K3 (inositol hexakisphosphate kinase 3), PC (pyruvate carboxylase), PLCG1 (phospholipase C gamma 1), and PRKCE (protein kinase C epsilon) [16].