Of note, liprin-α1 affects cancer cell spreading, the distribution of cell surface β1-integrins [14], and regulates cell edge dynamics and focal adhesion assembly in motile epithelial cancer cells via proteins including vimentin, ERC1 (ELKS/RAB6-interacting/CAST family member 1) and β1-integrin [12, 15]. Here, ERC1 is linked to cancer.