Since the reduction of prefrontal cortical volume and hallucinations are also associated with the susceptibility gene for schizophrenia and schizoaffective disorder, DISC1 [49], studies of the relationship between behavioral/cognitive deficits and hallucinations of schizophrenia are critical for understanding the pathopsychological processes and the endophenotype of this mental disorder [3, 53, 54]. The gene discussed is DISC1; the disease is schizophrenia.