Additionally we identified other dog-like genes known to be involved in immune functions, such as those coding for the immunity-related beta-defensins (CBDs and DEFB119) and those responsible for cellular responses and DNA repair (ARID1B, ASCC3, HM13, MGST2, MARCH7), and tumor suppression (UNC5C), that were identified to be hosted in key-differentiating regions for dog domestication [68]. The gene discussed is UNC5C; the disease is neoplasm.