Regarding the prediction of 28-day mortality, the area under the ROC curve for MPO-DNA on days 1, 3, and 7 of sepsis was 0.66 (p = 0.054, 95% CI 0.51–0.82), 0.74 (p = 0.005, 95% CI 0.33–0.77), and 0.83 (p = 0.0004, 95% CI 0.70–0.97), respectively (Fig. 5). Here, MPO is linked to Sepsis.