CCR6 and Psoriasiform dermatitis: CCR6 deficient mice had failed to develop psoriasiform dermatitis in skin following IL-23 injections, because IL-23 is a growth and differentiation factor of TH17 cells and hence a typical driver of TH17 mediated inflammation, validated by previous research showing that recombinant IL-23 injections given to mice skin results in psoriasiform dermatitis that mimics human psoriasis in as short a period as 5 days.