Luedke et al. [11] reported that BAX−/− mice exhibited reduced anxiety on the EPM when compared to WT controls, while MOAP-1−/− mice did not appear to have an altered anxiety state (Fig. 1e–g), suggesting that MOAP-1 and BAX deficiencies may not lead to identical effects on programmed cell death and thus differing effects on functional parameters. This evidence concerns the gene BAX and Anxiety.