Carcinoma‐associated fibroblasts of epithelial malignancies have been shown to express fibroblast activation protein‐α (FAP).34 In pancreatic cancer, high FAP expression in tumors correlates with worse prognosis.34, 48 Kraman et al49 further investigated the potential of FAP to have immunosuppressive properties in the tumor microenvironment using a transgenic mouse model depleted of FAP‐positive cells. This evidence concerns the gene FAP and carcinoma.