EPO and cancer: Agents such as corticosteroids, erythropoietin, angiogenic inhibitors (e.g., thalidomide, sunitinib, bevacizumab, and lenalidomide), and tyrosine kinase inhibitors, which are essentially administered as adjuvants in the treatment of cancer patients, have been shown to increase the risk of MR-ONJ when used concomitantly with bisphosphonates or denosumab [32, 33].