HDAC3 and non-small cell lung carcinoma: KDM2A also transcriptionally repressed the histone deacetylase 3 (HDAC3) by demethylating H3K36me2 at the HDAC3 promoter, thereby up-regulated HDAC3 target genes including the cell invasion-associated NANOS1 and the cell cycle-related CDK6 in KDM2A-overexpressing NSCLC cells [106].