It was shown that mRNA expression of GATA3 was increased in CRSwNP patients compared with CRSsNP and control groups (Pv < 0.0001 for CRSwNP vs. controls, Pv = 0.001 for CRSsNP vs. controls) (Fig. 5). This evidence concerns the gene GATA3 and chronic rhinosinusitis without nasal polyps.