CD4 and chronic rhinosinusitis without nasal polyps: CRSwNP group showed enhanced infiltration of CD4+ T cells into the sinonasal mucosa in comparison to CRSsNP group and controls (Pv < 0.0001 for CRSwNP vs. controls, Pv = 0.016 for CRSsNP vs. controls, and Pv = 0.006 for CRSsNP vs. CRSwNP) (Figs. 1 and 2, Table 3).