FUS and amyotrophic lateral sclerosis: This has been seen in e.g., most TDP-43- and tau-negative FTLD cases, as well as in some cases of juvenile ALS with basophilic inclusions and a subtype of FTLD-FUS, also with basophilic inclusion bodies (Huang et al., 2010; Urwin et al., 2010; Matsumoto et al., 2015).