KCNH2 and cancer: A similar approach might be applied to VEGF-A whose high expression is associated with poor prognosis [36]: in fact, we showed that in colorectal [21] and gastric [18] cancers hERG1 expression is significantly associated with VEGF-A expression and the combined therapy with bevacizumab and hERG1 blockers impairs tumor growth in mouse models [18].