KDR and Miyoshi myopathy: Bortezomib and zoledronic acid display distinct and synergistic activities on bone marrow macrophages in MM patients, inhibiting macrophage proliferation, adhesion, migration, and expression of angiogenic cytokines, angiogenesis on Matrigel, VEGFR-2 and ERK1/2 phospho-activation as well as nuclear factor kB (NF-kB) [62].