Yang et al. [60] observed decreased protein expression of HIF-1α, vascular endothelial growth factor-A (VEGF-A), and glucose transporter type 1 (GLUT1) in human breast cancer MCF-7 cells that were treated with a combination of hypoxia and non-toxic nanosilver treatment, as compared to cells treated only with hypoxia [60]. The gene discussed is VEGFA; the disease is breast cancer.