LTA and neoplasm: Statistical evaluation of the ultrastructural samples highlighted the main effects of combined TNF-β, 5-FU and resveratrol treatment in promoting and synergistically enhancing apoptosis in both HCT116 and HCT116R cells compared to control tumor cultures (Figure 4I,II) suggesting that resveratrol may inhibit inflammation and sensitize 5-FU in the chemoresistant cell line even under pro-inflammatory condition with TNF-β.