OSA subjects, BMI, fat mass, fat free mass, % body fat, WC, HC, MTC, subscapular, thigh, TG, TC, LDL, very low density lipoprotein- cholesterol (VLDL-C), ALT, AST, ALK, fasting insulin, hs-CRP and IL-6 levels were significantly increased in T/T genotype as compared to other genotypes. The gene discussed is CRP; the disease is obstructive sleep apnea syndrome.