When a subset of RA patients with slight periodontitis were randomly selected from the original study population, the RA patients presented higher levels of inflammation indexes GI and BOP, despite the lower levels of PI, PPD, and CAL and compatible levels of anti-TdEno and anti-ENO1 antibodies compared to non-RA subjects (Supplementary Table 2 and Supplementary Figure 2). The gene discussed is ENO1; the disease is rheumatoid arthritis.