TTR, known as prealbumin, has a major role in the transport of thyroxine and retinol as a transporter.25 Serum TTR might be a sensitive indicator in assessing liver dysfunction in acute liver diseases.26 Transferrin was also reduced in chronic hepatitis C and hepatitis B.27 Compared to the control group, TTR dropped to 0.85 in AIH, and later continued to decrease to 0.68 in AIC. This evidence concerns the gene TF and Decreased liver function.