TET3 and melanoma: Recent studies suggested that the expression of TET 2 and TET3 might be impaired under pathological conditions, ie haematological malignancies, melanoma and/or neurodegeneration.46, 47 However, it should be taken into account that our data concerns the fifth day of osteogenesis, and TET proteins may be switched on earlier in the AZA/RES group because epigenetic alternations are necessary for the differentiation process.