MEFV and familial Mediterranean fever: Main research questions were to show (i) if the changes in gut microbiota of FMF patients, primarily associated with the M694V/V726A pyrin inflammasome mutations, could lead to overgrowth of gut C. albicans of the patients and (ii) if colchicine/probiotic could effect on gut microbiota of patients through the regulation of NLRP inflammasomes.