Nineteen genes were shared by AD and hypertension, namely ABCB1, AHR, APOE, BCL2, CAT, CRP, ESR1, F2, GPX1, GSK3B, IL1B, LEP, MME, MTOR, NOS2, NOS3, PON1, SOD1, and SOD2. The gene discussed is ESR1; the disease is Hypertension.