MAOB and Alzheimer disease: In contrast, MAO-B activity was increased in AD samples in both cortex (P = 0.0009) and hippocampus (P = 0.0005), with contributions from both sexes (cortex: males, P = 0.0631 and females, P = 0.0218; hippocampus: males, P = 0.0331 and females, P = 0.0052) (Figure 1).