CDH1 and breast lobular carcinoma: Thus, grafted 4T1 and MMT tumors develop predominantly collective invasion of the mammary tissue, and this is consistent with the dominating collective invasion patterns found in human samples of both E-cadherin-positive ductal and E-cadherin-negative lobular breast carcinoma (Bronsert et al., 2014; Cheung et al., 2013; Khalil et al., 2017).