Recently, optical coherence tomography (OCT) in 4 patients with KIF11 mutations and microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability revealed atrophic maculae and disruption of the photoreceptor inner segment ellipsoid and the outer retinal bands.5 Foveal hypoplasia, retinal pigment epithelium (RPE) thinning, and a disruption of the ellipsoid zone (EZ) also have been found.12 In addition, children with congenital Zika syndrome showed retinal and choroidal thinning.13 This evidence concerns the gene KIF11 and microcephaly.