We also treated X‐ALD mouse models (Abcd1− and Abcd1−/Abcd2−/− mice) with dimethyl fumarate (DMF, BG‐12, Tecfidera), an NRF2 activator (Linker et al, 2011; Scannevin et al, 2012), that is a currently approved medication for relapsing‐remitting multiple sclerosis (Fox et al, 2012; Gold et al, 2012). This evidence concerns the gene NFE2L2 and adrenoleukodystrophy.