In the current study, we found that the predicted target genes of differentially expressed lncRNAs in moDCs included cytokines and chemokines, especially IL-6, CXCL10, IL-10, CXCL2, etc. We also observed that the differentially expressed mRNAs in moDCs of SLE patients were enriched in the process of cell migration and chemokine activity and in the pathways of cytokine-cytokine receptor interaction. The gene discussed is IL6; the disease is systemic lupus erythematosus.