Taking advantage of the tumors predominantly composed of CD24+CD29high cells, we transplanted 6 × 104 FACS-sorted Lin− cells (depleted of hematopoietic and endothelial cells) from a p18−/−;Brca1MGKO tumor and a p16−/−;Brca1MGKO tumor into eight MFPs of NSG mice (four for each cell type). This evidence concerns the gene CDKN2C and neoplasm.