Because the number of cells with mesenchymal features varies in different BRCA1-deficient tumors, we screened a panel of primary p18−/−;Brca1MGKO tumor cells by FACS for expression of Vim and identified at least two types of p18−/−;Brca1MGKO tumor cells, and in one of these, Vim-positive cells constituted 30–65% of the total tumor cells (type 1) and in the other, Vim-positive cells constituted > 90% of the total cells (type 2) (Fig. 3d-h and Additional file 6: Figure S6C). The gene discussed is VIM; the disease is neoplasm.