Other statistically significant sites included cg12978433 and cg18956481 in CYP24A1, cg09253762 and cg16984335 in CYP27B1, cg18482822, cg05072492, cg11035813, cg25588697, and cg12474705 in NADSYN1/DHCR7, and cg14854850 and cg10592901 in VDR. As we have previously reported that the protective association between 25(OH)D and breast cancer appears to be limited to postmenopausal women [3], we present postmenopause-specific analyses in Additional file 1: Tables S4 and S5 and Figure S1.The results were largely consistent with the analyses that included all breast cancers. This evidence concerns the gene CYP27B1 and breast cancer.